Cystic fibrosis is a hereditary disease that affects the entire body, causing progressive disability and early death. Cystic fibrosis affects the entire body and impacts growth, breathing, digestion, and reproduction. Difficulty breathing and insufficient enzyme production in the pancreas are the most common symptoms.
The Pancreas of patients with Cystic Fibrosis fails to produce enough enzymes that are necessary to break down food. As a result the food eaten retains its fats and most of its nutrients as it passes through the body.
The bronchial tubes in the lungs also malfunction and produce a thick, sticky mucus. Germs multiply in this mucus and cause respiratory infection such as pneumonia, accompanied by a cough and high fever that is more severe than normal.
A multitude of other symptoms, including sinus infections, poor growth, diarrhea, and potential infertility (mostly in males) result from the effects of cystic fibrosis on other parts of the body. Patients with Cystic Fibrosis also sweat profusely and their perspirations also contains an unusually high percentage of salt.
Cystic fibrosis is the most common life-limiting recessive disease among people of European heritage. Two copies of the recessive mutated gene, one from each parent is needed by the human body to develop Cystic Fibrosis.
Because cystic fibrosis testing is expensive, testing is often performed on just one parent initially. If that parent is found to be a carrier of a CFTR gene mutation, the other parent is then tested to calculate the risk that their children will have cystic fibrosis. Cystic fibrosis can result from more than a thousand different mutations and, as of 2006, it is not possible to test for each one. Most commercially available tests look for 32 or fewer different mutations.
Couples who are at high risk for having a child with cystic fibrosis; i.e. cystic fibrosis has developed in family members, will often opt to perform further testing before or during pregnancy. After birth cystic fibrosis may be diagnosed in newborn with sweat testing, or genetic testing.
Most states and countries do not screen for cystic fibrosis routinely at birth. Children with cystic fibrosis typically do not gain weight or height at the same rate as their peers and occasionally are not diagnosed until investigation is initiated for poor growth. Males tend to have a longer life expectancy than females but the reason is unknown.
Use a mask nebulizer and other inhalations treatments are the most common forms of treatments for cystic fibrosis. The goal is the treating and limiting the amount of lung damage caused by thick mucus and infection. Albuterol and ipratropium bromide are inhaled to increase the size of the small airways by relaxing the surrounding muscles. As lung disease worsens, breathing support from machines may become necessary.
Most individuals with cystic fibrosis take additional amounts of vitamins A, D, E, and K and eat high calorie meals.
Common Vitamins and over the counter products can help with treating Cystic Fibrosis such as Vitamin E, Vitamin K, Vitamin A, Lactase Enzyme, Papaya, Protein Tablets, Vitamin B, Amino Acid and L-Carnitine.
Dr. Harry Schwachman reported "most patients with cystic fibrosis have low levels of vitamin E". Vitamin E protects lung tissue form inhaled pollutants and aids the functioning of the immune system.
Vitamin K helps the blood to clot after and injury.
A number of studies have suggested that taking antioxidants such a Vitamin A reduces the risk of bronchoconstriction. Vitamin A is stored in the liver and fat cells of the human body and can reach toxic levels. DO NOT take more than the recommended dosage of Vitamin A.
Lactase Enzyme makes milk products more readily digestible.
Papaya contains lipase, which assists in Fat and Cellulose digestion.
Protein tablets increase protein intake.
All of the different Vitamin Bs taken together as B-Complex work together as a team to perform vital biological processes, such as energy production and efficient metabolic function. Vitamin B boost energy levels and help fight fatigue.
Amino Acid help regulate growth, digestion and maintaining the body's immune system.
L-Carnitine is essential for the body's ability to turn food into energy. L-Carnation increases energy at the cell level by increased fat burning, increases the body's ability to remove toxic disease-causing compounds and helps cells live longer.
Always consult your doctor before using this information.
This Article is nutritional in nature and not to be construed as medical advice.
About the Author
David Cowley has created over 50 articles about the relationship between diseases and vitamins. For other Articles on Diseases and Vitamin Needs feel free to visit my Web Site at http://www.dfcinvestment-team.com/
Thursday, April 19, 2007
Tuesday, November 28, 2006
Supplements Cystic Fibrosis
Supplements Important to Cystic Fibrosis Patients by Steven Godlewski
Cystic Fibrosis or CF is an inherited disease that affects the normal movement of salt (sodium chloride) into and out of certain cells, including those that line the lungs and pancreas. This results in thick, sticky mucus and other secretions. The mucus clogs the lungs, causing breathing problems. It also provides a breeding ground for bacteria to grow. This leads to frequent lung infections, which eventually damage the lungs and contribute to early death.
Thick digestive fluids also may clog ducts leading from the pancreas to the small intestine. This prevents the fluids from reaching the small intestine, where they are needed to digest food. This can cause digestive problems and slow growth. Some CF patients also suffer from poor liver function which may eventually become chronic liver disease.
Malabsorption of fat soluble vitamins is likely in most patients with cystic fibrosis, especially for those who are pancreatic insufficient. Vitamins A, D and E have been found to be deficient in early diagnosed infants as well as older patients. Different levels of these vitamins are prescribed depending on the age of the patient, whether the patient is pancreatic insufficient or sufficient and other health factors that can be affected by cystic fibrosis. Vitamin K may also be prescribed under certain conditions.
The recommended daily supplements which usually achieve normal plasma levels in infancy are vitamin A 4000 iu (120 mcg), vitamin D 400 iu (10 mcg) and vitamin E 37 - 75 iu (25 - 50 mg). The recommended doses for children over 1 year of age are vitamin A 8000 iu, vitamin D 800 iu and vitamin E 100 - 200 mg.
These doses are considerably higher than the usual dietary intake and generally are adjusted to meet the needs of the patient as they get older. Vitamin K is generally prescribed for those cystic fibrosis patients who suffer from liver disease or who are going to undergo a surgical procedure, or whose blood tests do not me certain standards.
* Vitamin A: Vitamin A deficiency may cause night blindness in older patients and can progress to severe xerophthalmia if not checked.
* Vitamin D: Vitamin D deficiency may cause rickets which is very rare and osteomalacia. Although in the past there is little clinical evidence of vitamin D deficiency is rare in cystic fibrosis new research and studies osteoporosis, osteopenia and low levels of vitamin D metabolites are being increasingly recognized in children and adults with cystic fibrosis.
* Vitamin E: Vitamin E deficiency may cause neurological problems in older CF individuals. Correction of vitamin E deficiency improves hemoglobin levels. Vitamin E is an antioxidant and protects cell membranes from oxidative damage. Because of this role vitamin E may be important in controlling the progression of lung disease in cystic fibrosis.
Recent studies have suggested that cystic fibrosis patients have inadequate antioxidants defenses to cope with certain stresses on their system. Pulmonary dysfunction in cystic fibrosis is associated with oxidative stress and higher levels of supplementation may be required.
* Vitamin K: Regular vitamin K supplements are not given unless there is chronic liver disease, a prolonged prothrombin time or an upcoming surgical procedure. Given any of these conditions an oral daily supplement of 5-10mg is given for a week prior to the procedure. Vitamin K is required for the formation of osteocalcin which is involved in bone metabolism.
As you can see vitamin supplementation is essential for Cystic Fibrosis patients. It is crucial for you to discuss any changes to your current vitamin regimen with your physician prior to adding, removing or changing the doses of any vitamins. The balance of vitamins in your system can be very delicate and should be closely monitored by your physician.
About the Author
Steven Godlewski is currently working with the staff at PillFreeVitamins.com He has an extensive background in nutrition as well as other health related fields. For more health-related articles see their website at: http://www.pillfreevitamins.com
Cystic Fibrosis or CF is an inherited disease that affects the normal movement of salt (sodium chloride) into and out of certain cells, including those that line the lungs and pancreas. This results in thick, sticky mucus and other secretions. The mucus clogs the lungs, causing breathing problems. It also provides a breeding ground for bacteria to grow. This leads to frequent lung infections, which eventually damage the lungs and contribute to early death.
Thick digestive fluids also may clog ducts leading from the pancreas to the small intestine. This prevents the fluids from reaching the small intestine, where they are needed to digest food. This can cause digestive problems and slow growth. Some CF patients also suffer from poor liver function which may eventually become chronic liver disease.
Malabsorption of fat soluble vitamins is likely in most patients with cystic fibrosis, especially for those who are pancreatic insufficient. Vitamins A, D and E have been found to be deficient in early diagnosed infants as well as older patients. Different levels of these vitamins are prescribed depending on the age of the patient, whether the patient is pancreatic insufficient or sufficient and other health factors that can be affected by cystic fibrosis. Vitamin K may also be prescribed under certain conditions.
The recommended daily supplements which usually achieve normal plasma levels in infancy are vitamin A 4000 iu (120 mcg), vitamin D 400 iu (10 mcg) and vitamin E 37 - 75 iu (25 - 50 mg). The recommended doses for children over 1 year of age are vitamin A 8000 iu, vitamin D 800 iu and vitamin E 100 - 200 mg.
These doses are considerably higher than the usual dietary intake and generally are adjusted to meet the needs of the patient as they get older. Vitamin K is generally prescribed for those cystic fibrosis patients who suffer from liver disease or who are going to undergo a surgical procedure, or whose blood tests do not me certain standards.
* Vitamin A: Vitamin A deficiency may cause night blindness in older patients and can progress to severe xerophthalmia if not checked.
* Vitamin D: Vitamin D deficiency may cause rickets which is very rare and osteomalacia. Although in the past there is little clinical evidence of vitamin D deficiency is rare in cystic fibrosis new research and studies osteoporosis, osteopenia and low levels of vitamin D metabolites are being increasingly recognized in children and adults with cystic fibrosis.
* Vitamin E: Vitamin E deficiency may cause neurological problems in older CF individuals. Correction of vitamin E deficiency improves hemoglobin levels. Vitamin E is an antioxidant and protects cell membranes from oxidative damage. Because of this role vitamin E may be important in controlling the progression of lung disease in cystic fibrosis.
Recent studies have suggested that cystic fibrosis patients have inadequate antioxidants defenses to cope with certain stresses on their system. Pulmonary dysfunction in cystic fibrosis is associated with oxidative stress and higher levels of supplementation may be required.
* Vitamin K: Regular vitamin K supplements are not given unless there is chronic liver disease, a prolonged prothrombin time or an upcoming surgical procedure. Given any of these conditions an oral daily supplement of 5-10mg is given for a week prior to the procedure. Vitamin K is required for the formation of osteocalcin which is involved in bone metabolism.
As you can see vitamin supplementation is essential for Cystic Fibrosis patients. It is crucial for you to discuss any changes to your current vitamin regimen with your physician prior to adding, removing or changing the doses of any vitamins. The balance of vitamins in your system can be very delicate and should be closely monitored by your physician.
About the Author
Steven Godlewski is currently working with the staff at PillFreeVitamins.com He has an extensive background in nutrition as well as other health related fields. For more health-related articles see their website at: http://www.pillfreevitamins.com
Saturday, June 03, 2006
Cystic Fibrosis Symptoms
Cystic Fibrosis Symptoms by Kent Pinkerton
Cystic fibrosis is a very serious disorder that is fatal if not treated properly. A defective gene causes thin body secretions, such as lung mucus, digestive juices, sweat and reproductive secretions, to become thick and sticky. Serious and life-threatening problems may arise due to this thickening. There is no permanent cure for cystic fibrosis yet, but symptomatic treatment is given.
When the lungs and airways are choked, the cystic fibrosis patient coughs and produces very thick sputum. He is short of breath and develops wheezing. Polyps may grow in the nasal passages. The frequency of sinus, chest infections, pneumonia and bronchitis increase.
As the digestive juices do not reach the intestine, due to blocked ducts from the pancreas and liver, the fats and protein are not digested. The stool is bulky, greasy and foul smelling. The cystic fibrosis patient may have excessive appetite but is undernourished and underweight, as the food is not digested properly for absorption. A trypsin test may indicate whether sufficient enzymes from the pancreas are available for digestion.
The sweat may taste salty. When we kiss a child with cystic fibrosis we can taste this excessive salt taste. To diagnose cystic fibrosis positively we measure this saltiness in sweat. Technicians coat an odorless chemical on a small area of the skin in the arm, and stimulate that area with electric current to produce copious sweat. This sweat should contain about 40 m mol/l in a normal person. Above 60 m mol/l of salt in a sweat test will confirm the diagnosis of cystic fibrosis. With cystic fibrosis patients the duct that connects the testes and vas deferens may get blocked. Most cystic fibrosis patients are sterile.
Treatment is mainly to ease the symptoms and lead a normal life in spite of the malady. Bronchodilators and mechanical vibrators keep the lungs and airways clear. Enzyme and vitamin supplements keep the digestive system near normal. With correct lifestyle management Americans are living to their 30 s and 40s with cystic fibrosis.
About the Author Cystic Fibrosis provides detailed information on Cystic Fibrosis, Cystic Fibrosis Symptoms, Causes Of Cystic Fibrosis, Cystic Fibrosis Treatments and more. Cystic Fibrosis is affliated with Living With COPD .
Cystic fibrosis is a very serious disorder that is fatal if not treated properly. A defective gene causes thin body secretions, such as lung mucus, digestive juices, sweat and reproductive secretions, to become thick and sticky. Serious and life-threatening problems may arise due to this thickening. There is no permanent cure for cystic fibrosis yet, but symptomatic treatment is given.
When the lungs and airways are choked, the cystic fibrosis patient coughs and produces very thick sputum. He is short of breath and develops wheezing. Polyps may grow in the nasal passages. The frequency of sinus, chest infections, pneumonia and bronchitis increase.
As the digestive juices do not reach the intestine, due to blocked ducts from the pancreas and liver, the fats and protein are not digested. The stool is bulky, greasy and foul smelling. The cystic fibrosis patient may have excessive appetite but is undernourished and underweight, as the food is not digested properly for absorption. A trypsin test may indicate whether sufficient enzymes from the pancreas are available for digestion.
The sweat may taste salty. When we kiss a child with cystic fibrosis we can taste this excessive salt taste. To diagnose cystic fibrosis positively we measure this saltiness in sweat. Technicians coat an odorless chemical on a small area of the skin in the arm, and stimulate that area with electric current to produce copious sweat. This sweat should contain about 40 m mol/l in a normal person. Above 60 m mol/l of salt in a sweat test will confirm the diagnosis of cystic fibrosis. With cystic fibrosis patients the duct that connects the testes and vas deferens may get blocked. Most cystic fibrosis patients are sterile.
Treatment is mainly to ease the symptoms and lead a normal life in spite of the malady. Bronchodilators and mechanical vibrators keep the lungs and airways clear. Enzyme and vitamin supplements keep the digestive system near normal. With correct lifestyle management Americans are living to their 30 s and 40s with cystic fibrosis.
About the Author Cystic Fibrosis provides detailed information on Cystic Fibrosis, Cystic Fibrosis Symptoms, Causes Of Cystic Fibrosis, Cystic Fibrosis Treatments and more. Cystic Fibrosis is affliated with Living With COPD .
Monday, May 29, 2006
Cystic Fibrosis Treatments
Cystic Fibrosis Treatments by Kent Pinkerton
Cystic fibrosis, which affects 30 ,000 American children and adults, is a multisystem disease caused by a defective gene. Presently only symptomatic management is possible, but there are very promising gene- therapy trials under way.
In the respiratory system the thin mucus lining becomes thick and sticky. In cystic fibrosis management, the primary treatment of the system is to thin or clear this mucus. Bronco dilators like albuterol are used to clear the clogged airways. Mucus thinning drugs delivered by aerosol, like pulmozyme, are helpful. The most effective way of clearing this mucus is by mechanically dislodging it. Clapping on the chest and back, with the head tilted on the edge of a table, is quite effective. There is an electrical clapper that does the job safely. There is an electrical inflatable vest that vibrates and dislodges the mucus. Infection is an ever-present risk with cystic fibrosis patients. Regular shots for pneumonia and influenza are very important. Bacterial infection is fought with newer antibiotics like TOBY, which delivers the medicine directly into airways with aerosols.
Because of the blocked ducts of the pancreas and liver, the enzymes and bile do not reach the intestine. Though the patient eats normally or even in excess, the fats and proteins are not digested. So the cystic fibrosis patient needs to have the enzymes supplemented with oral pancreatic enzymes. There is also the need to take vitamins, especially the fat-soluble ones. If lung function is completely damaged, the only alternative would be lung transplantation. This would involve many factors, like the availability of a donor and the patient's present health, prior to undergoing major surgery.
The Cystic Fibrosis Foundation has 115 centers all over America, and provides guidelines and advice. They support many studies to find gene therapy to cure cystic fibrosis. The target is to add normal genes to the cells of the airways to prevent further damage. Biotech laboratories produce healthy genes, which need to be delivered to the appropriate cells. These vectors, or delivery systems, are the key areas of research to combat cystic fibrosis. One method that is actively pursued is to modify the common cold virus to carry the healthy genes into the correct cells. On another track, the DNA molecules are compacted to their minimum size and delivered directly to the relevant cells without the need for a carrier such as a virus. This technology is called PLAS min.
As this gene therapy experiments are at an advanced stage, the cystic fibrosis sufferers can hope for a permanent cure in the near future.
About the Author
Cystic Fibrosis provides detailed information on Cystic Fibrosis, Cystic Fibrosis Symptoms, Causes Of Cystic Fibrosis, Cystic Fibrosis Treatments and more. Cystic Fibrosis is affliated with Living With COPD .
Cystic fibrosis, which affects 30 ,000 American children and adults, is a multisystem disease caused by a defective gene. Presently only symptomatic management is possible, but there are very promising gene- therapy trials under way.
In the respiratory system the thin mucus lining becomes thick and sticky. In cystic fibrosis management, the primary treatment of the system is to thin or clear this mucus. Bronco dilators like albuterol are used to clear the clogged airways. Mucus thinning drugs delivered by aerosol, like pulmozyme, are helpful. The most effective way of clearing this mucus is by mechanically dislodging it. Clapping on the chest and back, with the head tilted on the edge of a table, is quite effective. There is an electrical clapper that does the job safely. There is an electrical inflatable vest that vibrates and dislodges the mucus. Infection is an ever-present risk with cystic fibrosis patients. Regular shots for pneumonia and influenza are very important. Bacterial infection is fought with newer antibiotics like TOBY, which delivers the medicine directly into airways with aerosols.
Because of the blocked ducts of the pancreas and liver, the enzymes and bile do not reach the intestine. Though the patient eats normally or even in excess, the fats and proteins are not digested. So the cystic fibrosis patient needs to have the enzymes supplemented with oral pancreatic enzymes. There is also the need to take vitamins, especially the fat-soluble ones. If lung function is completely damaged, the only alternative would be lung transplantation. This would involve many factors, like the availability of a donor and the patient's present health, prior to undergoing major surgery.
The Cystic Fibrosis Foundation has 115 centers all over America, and provides guidelines and advice. They support many studies to find gene therapy to cure cystic fibrosis. The target is to add normal genes to the cells of the airways to prevent further damage. Biotech laboratories produce healthy genes, which need to be delivered to the appropriate cells. These vectors, or delivery systems, are the key areas of research to combat cystic fibrosis. One method that is actively pursued is to modify the common cold virus to carry the healthy genes into the correct cells. On another track, the DNA molecules are compacted to their minimum size and delivered directly to the relevant cells without the need for a carrier such as a virus. This technology is called PLAS min.
As this gene therapy experiments are at an advanced stage, the cystic fibrosis sufferers can hope for a permanent cure in the near future.
About the Author
Cystic Fibrosis provides detailed information on Cystic Fibrosis, Cystic Fibrosis Symptoms, Causes Of Cystic Fibrosis, Cystic Fibrosis Treatments and more. Cystic Fibrosis is affliated with Living With COPD .
Sunday, May 07, 2006
Sinus Cystic Fibrosis Infection: a Closer Look
Submitted by: marlonmj
A Printing Press
Have you heard of the infection called Sinus Cystic Fibrosis Infection? From the name itself it sounds for a serious ailment isn't it? What is this all about and how does it affects future sufferers? Let's try to figure out how!
According to scientific research Sinus cystic fibrosis infection is an inherited disorder of the exocrine glands, affecting children and young people. It is caused by a genetic abnormality in the sinus cystic fibrosis infection transmembrane conductance regulator gene that results in the disruption of chloride transfer across cell membranes. As a consequence, chloride ions build up in the cells of the lungs and other organs.
Moreover, water stays inside the cells to dilute the chloride rather than being drawn out of the cells by normal chloride movement and the normal secretions of the organs thicken. When the mucus in the exocrine glands becomes thick and sticky and eventually blocks the ducts of these glands especially in the pancreas, lungs, and liver which will soon be forming cysts. As a result this causes the sweat glands to secrete excessive salt, causing heat prostration in hot weather.
How can we detect if we acquire such infection?
Well there are symptoms varying according to the severity of the condition and the glands involved. Usually, it includes a distended abdomen diarrhea bulky, foul-smelling stools and malnutrition. In the long run, medical problems include nasal polyps and sinus disease, repeated respiratory infections, infertility, liver disease, and diabetes. Diagnosis is confirmed by a sweat test or measurement of transmembrane potential.
Accordingly, this is a cruel and deadly disease that affects almost every systems of our body like the respiratory system, the digestive system, endocrine system and reproductive system. This creates a disease complex with a wide range of disorders that can ultimately include chronic obstructive pulmonary disease, cystic fibrosis-associated liver fibrosis, diabetes mellitus, cholelithiasis, and arthritis.
Treatment consists of dietary adjustment (low fat high calorie) and the administration of vitamins, pancreatin, and antibiotics to ward off secondary infections. Special measures are necessary to decrease the viscosity of pulmonary secretions aerosol application of recombinant human dbase, an enzyme that digests the sticky extra cellular DNA that helps form these viscous secretions, was approved in 1993. In some cases lung transplantation is helpful. The identification of the abnormal gene (1989) paved the way for gene therapy aimed at altering the genetic structure by transferring to the patient cells with normal genes.
Identification of the genes has also made tests for genetic screening and diagnosis possible. Evolutionary biologists have suggested that the gene that must be inherited from both parents to cause the disorder, affords carriers some protection against cholera, a disease that kills through profound loss of fluids.
Health is wealth they say. Monitoring our health should be our primary concern. Staying away from any infections by living a healthy life is the best solution to fight SINUS CYSTIC FIBROSIS INFECTION!
For additional information and comments about the article you may log on to http://www.sinusinfectionproblems.com
A Printing Press
Have you heard of the infection called Sinus Cystic Fibrosis Infection? From the name itself it sounds for a serious ailment isn't it? What is this all about and how does it affects future sufferers? Let's try to figure out how!
According to scientific research Sinus cystic fibrosis infection is an inherited disorder of the exocrine glands, affecting children and young people. It is caused by a genetic abnormality in the sinus cystic fibrosis infection transmembrane conductance regulator gene that results in the disruption of chloride transfer across cell membranes. As a consequence, chloride ions build up in the cells of the lungs and other organs.
Moreover, water stays inside the cells to dilute the chloride rather than being drawn out of the cells by normal chloride movement and the normal secretions of the organs thicken. When the mucus in the exocrine glands becomes thick and sticky and eventually blocks the ducts of these glands especially in the pancreas, lungs, and liver which will soon be forming cysts. As a result this causes the sweat glands to secrete excessive salt, causing heat prostration in hot weather.
How can we detect if we acquire such infection?
Well there are symptoms varying according to the severity of the condition and the glands involved. Usually, it includes a distended abdomen diarrhea bulky, foul-smelling stools and malnutrition. In the long run, medical problems include nasal polyps and sinus disease, repeated respiratory infections, infertility, liver disease, and diabetes. Diagnosis is confirmed by a sweat test or measurement of transmembrane potential.
Accordingly, this is a cruel and deadly disease that affects almost every systems of our body like the respiratory system, the digestive system, endocrine system and reproductive system. This creates a disease complex with a wide range of disorders that can ultimately include chronic obstructive pulmonary disease, cystic fibrosis-associated liver fibrosis, diabetes mellitus, cholelithiasis, and arthritis.
Treatment consists of dietary adjustment (low fat high calorie) and the administration of vitamins, pancreatin, and antibiotics to ward off secondary infections. Special measures are necessary to decrease the viscosity of pulmonary secretions aerosol application of recombinant human dbase, an enzyme that digests the sticky extra cellular DNA that helps form these viscous secretions, was approved in 1993. In some cases lung transplantation is helpful. The identification of the abnormal gene (1989) paved the way for gene therapy aimed at altering the genetic structure by transferring to the patient cells with normal genes.
Identification of the genes has also made tests for genetic screening and diagnosis possible. Evolutionary biologists have suggested that the gene that must be inherited from both parents to cause the disorder, affords carriers some protection against cholera, a disease that kills through profound loss of fluids.
Health is wealth they say. Monitoring our health should be our primary concern. Staying away from any infections by living a healthy life is the best solution to fight SINUS CYSTIC FIBROSIS INFECTION!
For additional information and comments about the article you may log on to http://www.sinusinfectionproblems.com
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